12+ hour, 35+ min ago  (142+ words) Results revealed that the primary composite outcome occurred among 40. 8% of the vitamin C cohort compared with 29. 7% in the placebo cohort (adjusted risk ratio [RR], 1. 28; P=0. 06). Although narrowly missing conventional statistical significance, the result crossed the trial's predefined futility/harm threshold,…...

12+ hour, 31+ min ago  (158+ words) Preterm infants born to mothers with asthma had more than twice the risk for developing treatment'warranted type 1 or type 2 retinopathy of prematurity (ROP) compared with those born to mothers without asthma, according to findings from a retrospective cohort study published…...

11+ hour, 32+ min ago  (147+ words) Q&A: Examining Racial Variation in Pain Management Across Breast, Prostate, and Pancreatic Cancers in Community Oncology First, the pain medications that we assessed were acetaminophen, nonsteroidal anti-inflammatory drugs, and opioids, and we were able to capture pain medications prescribed within…...

1+ day, 6+ hour ago  (109+ words) James F. Howard Jr. , MD "This transcript has been edited for clarity. The responses that we did see in many of our patients were extremely gratifying, very similar to what we saw in ADAPT and ADAPT+that's one aspect. The other…...

1+ week, 18+ hour ago  (297+ words) Daniel C. Belz, MD, MPH Therefore, finding that a mechanism through which diet, perhaps through isoflavones, which we've seen previous evidence in lab work, decreases platelet inflammation and platelet activation, how these compounds in a diet could conceivably affect COPD through…...

3+ day, 47+ min ago  (167+ words) Maternal respiratory syncytial virus prefusion F (RSVpre F) vaccination during pregnancy dropped the risk for hospitalization for RSV-associated acute respiratory illness (ARI) and lower respiratory tract disease (LRTD) in young infants by nearly 70%, according to real-world data in JAMA Network Open....

2+ day, 20+ hour ago  (294+ words) One in Three Patients With Thyroid Abnormalities During Pregnancy Develop Overt Hypothyroidism Approximately one in three people who had thyroid abnormalities during pregnancy went on to develop overt hypothyroidism within 25 years of follow-up, according to a study published in the…...

2+ day, 20+ hour ago  (218+ words) Candida infections are uncommon but often severe during secukinumab treatment, underscoring the need for early monitoring and ongoing pharmacovigilance, according to a pharmacovigilance study published in BMC Infectious Diseases. Researchers used data from the US Food and Drug Administration Adverse…...

3+ day, 4+ hour ago  (232+ words) In earlier trials and an interim analysis of the phase 3 Opti TROP-Lung04 trial, sac-TMT showed survival benefits in patients with EGFR-TKI'resistant, EGFR-mutated advanced NSCLC. In this study, researchers reported the prespecified final analysis of progression-free survival and the preplanned interim…...

3+ day, 2+ hour ago  (410+ words) Cindy Salm Bauer, MD Peanut allergy, which affects 2% to 3% of children in high'income countries, has historically been managed with strict avoidance; however, both oral immunotherapy (OIT) and probiotic peanut oral immunotherapy (PPOIT) are equally cost-effective, according to findings from an…...