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News

mdpi.com
mdpi.com > 2076-16/16/3417 > 8161

Applied Sciences, Vol. 16, Pages 8161: Pelargonium graveolens L’Hér. in Traditional and Contemporary Medicine: Phytochemistry, Pharmacology, and Molecular Mechanisms

27+ min ago   (523+ words) Pelargonium graveolens L’Hér. is a widely distributed aromatic plant that has been utilized in traditional medicine for an extended period. It is currently experiencing a surge in popularity in modern phytotherapy. The ethnopharmacological uses of this species include treatment of…...

mdpi.com
mdpi.com > 2076-16/16/3417 > 8160

Applied Sciences, Vol. 16, Pages 8160: Risk-Aware Density–Boundary Graph Reweighting for Rare Event Detection in Intelligent Risk Monitoring Systems

1+ hour, 14+ min ago   (417+ words) Rare-event detection is a critical task in intelligent risk monitoring systems, where missed minority events may lead to financial loss, security threats, or operational failures. Existing imbalance-handling methods frequently apply one class-level correction and therefore ignore the heterogeneous geometric roles…...

mdpi.com
mdpi.com > 2076-16/16/3417 > 8159

Applied Sciences, Vol. 16, Pages 8159: Lycopene Nanoencapsulation and Cancer Treatment: A Systematic Review of Preclinical Evidence

1+ hour, 14+ min ago   (507+ words) Lycopene is a natural compound with significant antitumor potential, although its poor bioavailability restricts its clinical application. To address this limitation, diverse nanoparticle-based delivery systems have been developed. This systematic review evaluated whether encapsulation improves the antitumoral efficacy of lycopene....

mdpi.com
mdpi.com > 2076-16/16/3417 > 8158

Applied Sciences, Vol. 16, Pages 8158: Quantum Horizons in Cancer Radiotherapy: Integrating DNA Damage Modeling, Radiobiology, and Emerging Treatment Technologies

1+ hour, 33+ min ago   (773+ words) Purpose: Marking the one hundredth anniversary of quantum mechanics in 2025, quantum science has become foundational for the development of contemporary technologies, enabling advances in sensing, imaging, computing, and materials engineering. Cancer radiotherapy, although traditionally developed within the scope of classical…...

mdpi.com
mdpi.com > 2076-16/16/3417 > 8157

Applied Sciences, Vol. 16, Pages 8157: Performance Analysis of a Modular Framework for Edge-Based Generative Conversational AI

2+ hour, 37+ min ago   (663+ words) This study presents a multi-tier framework for deploying multi-modal Conversational AI on edge devices, spanning from constrained ultra-low-power systems to high-performance edge workstations. Utilizing an automated model discovery process and a modular benchmarking testbed, the research demonstrates that real-time, fully…...

mdpi.com
mdpi.com > 2076-16/16/3417 > 8156

Applied Sciences, Vol. 16, Pages 8156: Stress Distribution in Different Permanent Fixed Restorative Materials with Different Connector Dimensions: A 3D Finite Element Analysis

2+ hour, 45+ min ago   (372+ words) The aim of this in vitro study is to evaluate the stress distribution of different definitive restorative materials designed with different connector dimensions using finite element analysis. Two adjacent prepared maxillary molars were designed digitally. Two-unit splinted fixed dental prostheses…...

mdpi.com
mdpi.com > 2076-16/16/3417 > 8155

Applied Sciences, Vol. 16, Pages 8155: A Study on Construction Control of Extra-Large-Span Asymmetric Variable-Cross-Section Tunnels

3+ hour, 20+ min ago   (618+ words) In the construction process of a super-long-span short-distance continuous variable cross-section tunnel, multiple geometric mutations along the alignment induce significant discontinuity and asymmetry in the mechanical response of the surrounding rock-support system, which differs significantly from that of conventional single-variable-section…...

mdpi.com
mdpi.com > 2076-16/16/3417 > 8154

Applied Sciences, Vol. 16, Pages 8154: Hybrid Rule-Based and Machine Learning Architecture for Reducing Alert Fatigue in Clinical Decision Support Systems

5+ hour ago   (396+ words) Clinical decision support systems operating in hospital environments generate large numbers of alerts based on continuously monitored clinical data. A major challenge in such systems is alert fatigue, caused by excessive numbers of notifications and unnecessary escalation of alert severity,…...

mdpi.com
mdpi.com > 2076-16/16/3417 > 8153

Applied Sciences, Vol. 16, Pages 8153: Predicting the Effect of Chemotherapy on the State of a Cancerous Tumor Using Fractal-Physical-Information Neural Networks

3+ hour, 16+ min ago   (371+ words) Understanding tumor dynamics under chemotherapy is important for improving the prediction of cancer progression and assessing treatment effectiveness. This paper proposes a numerical modeling approach based on a fractal physics-informed neural network (fPINN) designed to solve nonlinear fractional-order differential equations…...

mdpi.com
mdpi.com > 2076-16/16/3417 > 8147

Applied Sciences, Vol. 16, Pages 8147: Factor-Based Assessment of Perceived Influences on Front-End Planning Quality in Local Public Construction Projects: Evidence from Tan Chau, Vietnam

23+ hour, 31+ min ago   (444+ words) Front-end planning is important for local public construction projects because deficiencies in surveys, design documentation, cost estimation, appraisal, and stakeholder coordination can lead to repeated revisions, approval delays, and cost adjustments. This study assessed practitioners’ perceived influences on front-end planning…...