11+ hour, 9+ min ago  (218+ words) The World Health Organization (WHO) has designated a network of regional training centers for biomanufacturing across all six WHO regions, which is intended to mark a major step forward in strengthening the global workforce needed to produce vaccines, biotherapeutics and…...

11+ hour, 3+ min ago  (216+ words) Zhang, also a member of Baylor's Dan L Duncan Comprehensive Cancer Center, is senior and corresponding author of the team's published paper in Cell, titled "Unbiased niche labeling maps immune-excluded niche in bone metastasis." During metastasis, cancer cells interact constantly…...

8+ hour, 35+ min ago  (486+ words) Serif Biomedicines alters structure and chemistry of genetic material to combine the advantages, and minimize the drawbacks, of m RNA and gene therapy What happens when the scalability and redosability of messenger RNA (m RNA) is combined with the durability…...

8+ hour, 53+ min ago  (256+ words) Transactivation domains (TADs) of transcription factors are enriched in intrinsically disordered regions (IDRs) that lack a stable three-dimensional structure. The plasticity of an IDR permits dynamic conformations that regulate cellular and biological functions." The new study developed"inhibitors"that bound…...

9+ hour, 51+ min ago  (247+ words) This work is published in APL Bioengineering, in a paper entitled, "Force-sensing mobile microrobotic grippers for gentle and precise bioassembly of cell spheroids." Integrating different types of spheroids into one culture is key for tissue engineering. But individual spheroids have…...

1+ day, 7+ hour ago  (502+ words) This comparison shows imaging of a blood-brain barrier model using a common Gaussian beam (top) versus the new Pencil beam method (bottom) which captures the entire volume and 3 D information in a single scan. [MIT] Scientists at MIT say they…...

1+ day, 6+ hour ago  (963+ words) By adapting a retron-based editing system from E. coli to 15 bacterial species, scientists reveal a genome editing platform that could accelerate studies of pathogens, microbial interactions, and engineered bacteria used in manufacturing. The post Retron-Powered Approach Enables Genome Editing Across Diverse…...

1+ day, 4+ hour ago  (550+ words) Sun Pharmaceutical Industries has agreed to acquire Organon, the women's health drug developer spun out of Merck & Co. , for $11. 75 billion in a deal intended to catapult the buyer into a top 25 global biopharma'top three in women's health'by growing its innovative…...

1+ day, 7+ hour ago  (1181+ words) Genetic Engineering and Biotechnology News Scientists headed by a team at MRC Laboratory of Medical Sciences (LMS) and Imperial College London have found that a new set of drugs can exploit a recently-revealed weakness in senescent'or "zombie-like'cells, a finding that…...

1+ day, 10+ hour ago  (410+ words) Genetic Engineering and Biotechnology News Kristina Pleitt is a senior staff scientist at Thermo Fisher Scientific with 15 years of experience in biopharmaceutical process development and manufacturing. Her expertise includes downstream process development, process scale-up, integrated continuous processing, and clinical and…...