7+ hour, 3+ min ago   (1314+ words) The research team discovered why the drug acts differently from others in its class. Losing weight can happen via two paths: eating less, or spending more energy. Today’s blockbuster GLP-1 drugs are well-known for their ability to help people eat…...

4+ day, 21+ hour ago   (428+ words) Improving CNS drug discovery outcomes means confronting a specific, well-documented problem: this therapeutic area fails more often, and takes longer to succeed, than almost any other in pharma, and a meaningful part of that problem traces back to studying brain…...

5+ day, 23+ hour ago   (353+ words) Somewhere in a grid of thousands of tissue images sits a pattern no one has named yet. Finding it by eye is no longer the plan. That is precisely what a discovery workflow needs to be built to find: patterns…...

5+ day, 23+ hour ago   (388+ words) A technique that takes one skilled scientist a full day per sample cannot become a pipeline tool. Automation is what actually changes that math. Our earlier coverage in The future of spatial biology depends on automation establishes the general case…...

6+ day, 6+ hour ago   (1593+ words) The approach offers a way to measure network-level therapeutic effects in living patients that conventional imaging analysis does not provide. Most of the recent progress in Alzheimer's disease therapeutics has centered on clearing amyloid from the brain. The approval of…...

6+ day, 6+ hour ago   (664+ words) Newborn babies exposed to HIV during delivery may be able to clear the virus for good with help from a combination of medicines. The case dashed the hopes of doctors and scientists around the world who thought that it had…...

1+ week, 1+ min ago   (659+ words) One exhaustion marker tells part of the story. Measuring four together, in the same place, tells a reader which combination might actually work. The most direct route to a better biomarker, current evidence suggests, is not necessarily a new individual…...

1+ week, 1+ day ago   (566+ words) The same cell can look like a different target depending on whether it is studied alone or in place. Two consequences follow directly from that loss, and both change how a target discovery team should read single-cell data. Validation is…...

1+ week, 5+ day ago   (165+ words) Drug Discovery News Explained: How can molecular biology teams scale therapeutic design with connected workflows? To keep pace with modern drug discovery, researchers need molecular biology approaches that can support complexity without slowing down the science. Molecular biology has long…...

1+ week, 6+ day ago   (1147+ words) New approaches aim to target infections while sparing the gut microbiome. This mismatch has prompted researchers to ask whether antibiotics could be made more precise — delivering drugs where they are needed while limiting exposure elsewhere in the body. The latter…...