1+ hour, 27+ min ago  (223+ words) Background Coronary atherosclerosis remains a leading cause of ischemic heart disease and cardiovascular morbidity and mortality. While its clinical burden is well described, less is known about how its economic burden, defined using absolute expenditures and relative measures such as…...

1+ day, 1+ hour ago  (152+ words) Common variable immunodeficiency (CVID) is a primary immunodeficiency characterized by hypogammaglobulinemia, impaired vaccine response, and increased susceptibility to infections. Advances in molecular genetics have enabled the identification of monogenic forms in an increasing proportion of patients. In this study, a targeted…...

1+ day, 1+ hour ago  (223+ words) Timely reperfusion is central to the management of ST-segment elevation myocardial infarction (STEMI), but dynamic coronary processes such as vasospasm may complicate primary percutaneous coronary intervention (PCI). We present a 50-year-old male with hyperlipidemia, active tobacco use, daily nicotine vaping,…...

1+ day, 1+ hour ago  (357+ words) Background: Neonatal intubation (NI) requires technical skill and can cause life-threatening complications when performed improperly. Trainee success at NI is substandard, and nearly half of graduating trainees do not achieve the desired competency by the end of residency. This issue…...

3+ hour, 8+ min ago  (166+ words) Maxillary sinus pneumatization following tooth loss can result in reduced vertical bone height in the posterior maxilla, limiting the available bone for dental implant placement. The lateral window sinus elevation technique allows access to the sinus cavity and elevation of…...

2+ hour, 20+ min ago  (330+ words) Background: Therapeutic immunomodulation using pulse methylprednisolone is one of the cornerstones of management in multisystem inflammatory syndrome in children (MIS-C). This study examines whether bradycardia was possibly methylprednisolone-induced and if the risk and time taken to develop or recover from…...

10+ hour, 34+ min ago  (217+ words) Primary neuroendocrine tumors (NETs) of the breast are a very rare type of tumor, originating from cells that make up the neuroendocrine system and produce peptides and amines. This type of tumor represents a very rare subtype of breast carcinoma,…...

1+ day, 1+ hour ago  (170+ words) Manasa Mula " Zachary Li " Taylor M. Gong " Eduardo D. Espiridion PSM: propensity score matching; DLX topiramate + duloxetine group; AMT topiramate + amitriptyline group; Std diff. : standardized (mean) difference, SD: standard deviation; T2 DM: type 2 diabetes mellitus. The five-year risk of psychiatric outcomes (Table 2) was significantly…...

1+ day, 1+ hour ago  (200+ words) Leptomeningeal carcinomatosis (LMC) remains a devastating complication of epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer despite the availability of central nervous system (CNS)-active EGFR tyrosine kinase inhibitors (TKIs). We report the case of a 77-year-old woman with…...

1+ day, 1+ hour ago  (339+ words) TFE3-rearranged renal cell carcinoma (TFE3-RCC) is a rare molecular subtype of renal cell carcinoma (RCC), characterized by Xp11. 2 translocations involving the TFE3 gene. It is more common in pediatric populations and is often associated with aggressive clinical behavior and diagnostic challenges. Given…...