15+ hour, 54+ min ago   (104+ words) Time-lapse optical microscopy captures the dynamic formation of a liquid–liquid phase-separated coacervate interface. Micro-coacervates spontaneously emerge, undergo budding and fusion, assemble into hierarchical coacervate structures, and eventually form a single giant micro-coacervate, illustrating active boundary remodeling during phase separation....

17+ hour, 58+ min ago   (44+ words) Graphic abstract: (IMAGE) EurekAlert! Brief description: ELFN1 interacts with the apical surface of mGlu7 and acts as a positive allosteric modulator by triggering a conformational change of the receptor. This enabled development of an ELFN1-derived peptide that regulates the activation of mGlu7....

17+ hour, 15+ min ago   (44+ words) image EurekAlert! A population of yolk sac-derived hepatic γδT cells develops in a thymus- and hematopoietic stem cell-independent manner. More on this News Release A yolk sac-derived hepatic γδ T cell subpopulation develops in a hematopoietic stem cell- and thymus-independent…...

16+ hour, 17+ min ago   (554+ words) In the rapidly evolving landscape of biological research, understanding the heterogeneity within cell populations has become a defining challenge. While genomics tells us what could happen and transcriptomics reveals what might be happening, proteomics shows us what is actually occurring…...

19+ hour, 52+ min ago   (112+ words) Toward the goal of elucidating the targeting mechanism of SUV39H2, this study demonstrates that RNA-binding is required for its chromatin recruitment. The lncRNA Gas5 was identified to direct SUV39H2 to genomic targets in ESCs, and the SUV39H2-Gas5 interaction is critical for heterochromatin maintenance and…...

18+ hour, 59+ min ago   (85+ words) image: Impact and workflow of drift correction on SMLM image reconstruction. view more Credit: Dalian University of Technology / Donghan Ma The review also discusses hybrid strategies that combine multiple methods, such as pairing real-time back-focal-plane axial focus locking with post-processing…...

1+ day, 17+ hour ago   (268+ words) Scientist Live Biotechnology company Amsbio’s biospecimens have been used in a large-scale immuno-oncology study analysing Fibroblast Activation protein (FAP) expression across 23 tumour types, contributing to new insights into biomarker development for cancer immunotherapies. Scientists at Roche Pharma Research used both…...

2+ day, 1+ hour ago   (10+ words) figure_generation chorescience.ai 4 public chores · 568 categorized trials...

2+ day, 9+ hour ago   (42+ words) Figure 2 (IMAGE) EurekAlert! Evolution of materials databases. Hao Li et al. Reporters may use these materials freely in news coverage with appropriate credit information. More on this News Release AI-powered closed-loop system could accelerate the discovery of energy materials...

2+ day, 9+ hour ago   (324+ words) Researchers at Queen Mary University of London and University of Cambridge in collaboration with colleagues at HHMI Janelia and NIH, have created some of the most detailed three-dimensional maps ever generated of human airway cells, revealing how the specialised cells…...