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Targeted Endovascular Infusion for Severe Thoracolumbar Pain Delivers Rapid Analgesia
1+ day, 3+ hour ago (234+ words) At a single center, the research team used a femoral transarterial approach to treat six patients (mean age, 73.5 years; 83% female) presenting with severe baseline spinal pain (83% mechanical thoracolumbar; 17% oncologic L2-3). Lesions spanned osteoporotic or insufficiency‑type compression fractures at L2, T10, T12/L2, and L1, along…...
Q&A: What the New CKM Guideline Means for Patient Care
1+ day, 12+ hour ago (697+ words) Chiadi Ndumele, MD, PhD, MHS Clinicians who manage obesity, diabetes, kidney disease, and heart disease received a new guideline that addresses the interconnections among these conditions. The guideline, issued jointly by the American Heart Association (AHA) and American College of…...
Tranexamic Acid Use in Major Noncardiac Surgery Cuts Transfusion Rates
1+ day, 12+ hour ago (184+ words) Our results align with and extend previous evidence supporting antifibrinolytic therapy in surgery,” wrote study author Ryan Zarychanski, MD, MSc, of the University of Manitoba, CancerCare Manitoba, and the George and Fay Yee Center for Healthcare Innovation, Canada, and colleagues....
Ruxolitinib Shows Efficacy in Atopic Dermatitis | www.PhysiciansWeekly.com
2+ day, 5+ hour ago (282+ words) Ruxolitinib Cream Efficacious in Moderate AD After Failure of Standard Topicals Adults with moderate atopic dermatitis (AD) who failed or could not tolerate topical corticosteroids (TCS) and topical calcineurin inhibitors (TCI) achieved significant clinical improvement with 1.5% ruxolitinib cream, according to…...
Dupilumab Shows Histologic & Endoscopic Benefit in Eosinophilic Gastritis
1+ day, 22+ hour ago (162+ words) Results revealed that at week 12, dupilumab produced a markedly greater reduction in the primary endpoint, relative change in mean gastric eosinophil count, compared with placebo (–50% vs –4%; difference –47 percentage points; P Treatment‑emergent adverse events occurred at similar rates in both…...
Simple Blood-Based Nomogram May Identify Children at Risk for Prolonged Epstein-Barr Virus Fever
2+ day, 5+ hour ago (283+ words) In a retrospective study of 791 immunocompetent children hospitalized with primary EBV infection, investigators developed and internally validated a nomogram using complete blood count findings obtained at presentation. The goal was to provide a simple and accessible tool for early risk…...
Study: Hormone Therapy Safe in Cervical Cancer
2+ day, 4+ hour ago (297+ words) Large Study Reinforces Hormone Therapy's Safety in Young Patients With Cervical Cancer Hormone therapy initiation after the first year of cancer treatment was associated with reduced morbidity and improved survival in patients with cervical cancer, according to a study published…...
CBT-I for Insomnia: A Target in Psychiatry
2+ day, 5+ hour ago (686+ words) CBT-I May Help Reframe Insomnia as a Treatment Target in Psychiatric Care Jessica Fink, LCSW-S (left), and Chelsie Rohrscheib, PhD (right) Insomnia disorder is common among patients with psychiatric disorders and can impact the effects and management of those disorders…...
Metabolic Reprogramming Framework Illuminates Sepsis-Associated Encephalopathy Pathophysiology
2+ day, 5+ hour ago (167+ words) Up to 70% of patients with sepsis experience sepsis-associated encephalopathy (SAE). This condition can be fatal and may cause long-term cognitive damage. Furthermore, sepsis-associated encephalopathy is a predictor of poor prognosis. Huang and colleagues also pointed to several therapeutic options. Metformin…...
Health Is Not a Partisan Issue: How Medicaid Cuts Impact Every American
2+ day, 6+ hour ago (604+ words) Alex McDonald, MD, CAQSM The question is not whether these changes will affect patients. The Congressional Budget Office (CBO) already confirmed that they will. The real question is whether the medical community and the American public will make themselves heard…...