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Challenges to Posttransplant Immunosuppression Adherence
1+ hour, 57+ min ago (187+ words) What are the leading barriers to immunosuppression adherence that you've observed? What practical methods can help busy clinicians identify these barriers within routine clinic visits or lab monitoring? What education points or tools have proven most effective for improving patient…...
Can Complement Inhibitors and Neonatal Fc Receptor Blockers Treat Generalized MG?
18+ hour, 24+ min ago (143+ words) Can Complement Inhibitors and Neonatal Fc Receptor Blockers Treat Generalized Myasthenia Gravis? In particular, the odds of achieving clinically meaningful improvements in Myasthenia Gravis Activities of Daily Living and Quantitative Myasthenia Gravis scores more than doubled (ORs 2. 7 and 3. 5). Meanwhile, the…...
Physicians" Understanding of AD and Related Dementias May Be Enhanced by Education
18+ hour, 45+ min ago (244+ words) Dementia is becoming increasingly common. Hence, there is a growing need for physicians and other medical professionals to expand their understanding of Alzheimer's disease (AD) and related dementias. The researchers used questionnaires to collect information from a cohort of 479 clinical…...
Status of Phase 4 Platform Trial of South Asian Patients With Primary Ig AN
19+ hour, 6+ min ago (139+ words) Previous studies have demonstrated an association between South Asian ethnicity and markedly more severe phenotype and rapid progression of Ig A nephropathy (Ig AN). Few pragmatic clinical trials have evaluated commonly available approved generic drugs as a long-term strategy to…...
Obinutuzumab Results Superior to Mycophenolate Mofetil in Phase 3 Nephrotic Syndrome Trial
18+ hour, 40+ min ago (338+ words) The most common pediatric glomerular disease worldwide is idiopathic nephrotic syndrome (INS). The efficacy of B-cell'depleting monoclonal antibodies for steroid minimization in frequently relapsing nephrotic syndrome (FRNS) or steroid-dependent nephrotic syndrome (SDNS) supports a pathogenetic role for B cells in…...
Strict Renal Resistance Cutoffs May Reduce Kidney Use
2+ day, 2+ hour ago (246+ words) From 2012 to 2023, rates of kidney nonuse in transplantation rose from 19% to 28%, due in part to increased reliance on hypothermic machine perfusion to assess terminal renal resistance. Elevated resistance is widely used as a marker of kidney quality and an indicator…...
MASLD, MASH, and the Role of SGLT2 Inhibitors: Clinical Implications
2+ day, 23+ hour ago (198+ words) And so that's why it's really important to think upstream and more thinking about prevention early on when steatosis is present. And I think by reducing the steatosis, the hope is that we'd be able to also reduce future incidents…...
Breastfeeding Inversely Linked to Asthma and Allergies Up to Young Adulthood
3+ day, 1+ hour ago (228+ words) Exclusive breastfeeding during a baby's first 4 months or longer is associated with reduced risk for childhood'onset asthma and Ig E sensitization into young adulthood. The findings, from a study by Inger Kull, Ph D, and colleagues, highlight the need to…...
Long Acting Anti'IL-4 R" Antibody for AD
3+ day, 16+ min ago (218+ words) These data were first presented by Jianzhong Zhang, MD, Ph D, of Peking University People's Hospital, Beijing China, at the 2026 American Academy of Dermatology Annual Meeting in Denver, Colorado, on March 28. At week 16, there was a significantly higher rate of…...
Can Dynamic Biomarkers Change Treatment Decisions?
2+ day, 23+ hour ago (476+ words) Docwire News Can Dynamic Biomarkers Change Treatment Decisions? Margaret Gatti'Mays, MD, MPH, examines whether dynamic biomarkers such as circulating tumor DNA (ct DNA) are ready to meaningfully change treatment decisions in breast cancer care. She outlines key practical challenges clinicians…...
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