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biotechniques. com > cancer-research > how-to-make-cancer-therapies-better-an-insight-into-the-distinct-roles-of-bet-proteins

How to make cancer therapies BETter: an insight into the distinct roles of BET proteins

3+ hour, 2+ min ago  (145+ words) Original story from the Max Planck Institute of Immunobiology and Epigenetics (Freiburg, Germany). Understanding the distinct roles of BET proteins could unlock a more targeted approach to cancer therapy. A new study from the Max Planck Institute of Immunobiology and…...

Bio Techniques
biotechniques. com > cell-and-tissue-biology > controlling-diabetes-without-insulin-injections-thanks-to-new-implant

Controlling diabetes without insulin injections thanks to new implant

1+ day, 3+ hour ago  (673+ words) Original story from Massachusetts Institute of Technology (MA, USA). Implantable islet cells could control diabetes without insulin injections, surviving in the body for at least 3 months and producing enough insulin to control blood sugar levels. This device, the researchers hope,…...

Bio Techniques
biotechniques. com > bioengineering-biophysics > snailing-colorectal-cancer-drug-delivery-once-and-for-all

Snailing colorectal cancer drug delivery, once and for all

1+ day, 21+ hour ago  (215+ words) Inspired by snails, a new drug delivery project has received a considerable funding boost. Cancer therapies are becoming increasingly advanced, but off-target, systemic effects still pose serious complications for doctors and patients alike, making the delivery of a critical dose…...

Bio Techniques
biotechniques. com > imaging > 4d-atlas-of-thousands-of-genes-offers-unparalleled-insight-into-embryogenesis

4 D atlas of thousands of genes offers unparalleled insight into embryogenesis

2+ day, 3+ hour ago  (499+ words) Original story from the University of Basel (Switzerland). How does a tiny cluster of cells become an embryo with a head, trunk and tail? And how do thousands of genes coordinate this development? A new imaging method makes it possible…...

Bio Techniques
biotechniques. com > cell-and-tissue-biology > takarabio_sptl_spatial_uncovering-the-cellular-origins-of-cancer-and-neurodevelopmental-disease

Uncovering the cellular origins of cancer and neurodevelopmental disease

2+ day, 3+ hour ago  (109+ words) In this interview, Jasmine shares the techniques she and her lab have developed to investigate the cellular processes underlying disease, some of the limitations of spatial technologies and data analysis tools and the mission of the Global Alliance for Spatial…...

Bio Techniques
biotechniques. com > biochemistry > shining-a-blue-light-on-an-overlooked-posttranslational-modification

Shining a blue light on an overlooked posttranslational modification

3+ day, 4+ hour ago  (257+ words) Original story from Rice University (TX, USA). A simple way to study a common but overlooked posttranslational modification has been developed, unlocking new insights into how proteins function Pyroglutamate occurs when a chemical reaction makes a ring at an amino…...

Bio Techniques
biotechniques. com > computational-biology > accelerating-drug-discovery-with-paradigm-shifting-ai-model

Accelerating drug discovery with "paradigm shifting" AI model

6+ day, 22+ hour ago  (415+ words) It's like a paradigm shift approach" to drive discovery: a new machine-learning model predicts how molecules will influence gene expression and has been used to pick out promising drug candidates for two tough-to-treat diseases. Identifying drugs that reverse the expression…...

Bio Techniques
biotechniques. com > microbiology > go-with-your-gut-exploring-the-microbiota-gut-brain-connection

Go with your gut: exploring the microbiota'gut'brain connection

1+ week, 1+ hour ago  (1017+ words) The far-flung organs of the gastrointestinal tract and the central nervous system are inextricably connected, and the growing body of scientific literature surrounding the "gut-brain axis" is increasingly demonstrating the role of the microbiome in this two-way communication. Impaired gut'brain…...

Bio Techniques
biotechniques. com > cancer-research > transforming-immune-cells-into-cancer-seeking-bloodhounds-to-eliminate-tumors

Transforming immune cells into cancer-seeking 'bloodhounds' to eliminate tumors

6+ day, 23+ hour ago  (584+ words) Original story from Stanford Medicine (CA, USA). Immune cells engineered to sense metabolic by-products secreted by cancer cells "follow their noses" to migrate to and infiltrate solid tumors in mice. A technique that transforms immune cells into cancer-seeking bloodhounds may…...

Bio Techniques
biotechniques. com > cell-and-tissue-biology > the-biotech-bi-weekly-cell-barcoding-compound-optimization-and-the-trillion-cell-atlas

The biotech bi-weekly: cell barcoding, compound optimization and the Trillion Cell Atlas

1+ week, 1+ day ago  (103+ words) A roundup of one of the industry's leading conferences for life sciences discovery and technology. Read the full release >>>" e Book | Cutting-edge techniques to enhance cancer drug discovery SLAS has introduced the 12 companies selected for the Innovation Ave NEW program…...

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