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Emergency diagnoses of medical conditions predict worse patient survival

3+ hour, 45+ min ago   (304+ words) Patients diagnosed with conditions after an emergency hospital admission or an emergency room visit face a higher risk of death than those diagnosed in non-emergency settings, according to a large population-based study by Emma Whitfield and colleagues from University College…...

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Diabetes study reveals differing health risks for men and women

3+ hour, 49+ min ago   (203+ words) In the years following type 2 diabetes diagnosis, women are more likely to develop mental health conditions, while men are more likely to develop cardiovascular and renal complications, according to a study published August 25th in the open access journal PLOS Medicine…...

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Scientists discover how neutrophils travel to infection sites without damaging healthy tissue

6+ hour, 11+ min ago   (405+ words) UMass Chan Medical School scientist Beth McCormick, PhD, and her team collaborated with researchers at the University of Bath to discover how neutrophils, the body's most abundant type of white blood cells, travel to infection sites without damaging healthy tissue....

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How generative AI improves hit identification in drug discovery

6+ hour, 50+ min ago   (1026+ words) Organizations that have successfully adopted generative AI have invested heavily in cleaning and curating their internal datasets, often covering decades of experimental work. This includes not just activity data, but extensive ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) profiles that…...

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Standard memory tests fail to detect post-chemotherapy brain fog

6+ hour, 39+ min ago   (121+ words) The researchers found that while survivors performed similarly to the control group on the word-pair test, they recalled fewer details in the story-based test. They concluded that standard clinical memory assessments can underestimate the real-world impact of chemotherapy-related memory impairments....

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Advancing peptide bioanalysis for drug development

8+ hour, 5+ min ago   (237+ words) High potency and increased specificity are just two of the properties that demonstrate the potential of peptide-based therapeutics as a drug class. View the case study With flexible partnering models tailored to our customers’ needs, we work with all Top…...

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The certification illusion: Why safety seals miss hidden chemical hazards

9+ hour, 22+ min ago   (298+ words) The finding comes on the heels of a companion study finding unlabeled chemicals in nearly all of 113 personal care and cleaning products tested. Most contained at least one unlabeled chemical with known or suspected health hazards, and one in four…...

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Study finds distinct patterns of innate immune activity in mental disorders

9+ hour, 46+ min ago   (901+ words) The immune system may also play a role in mental disorders. Scientists are investigating these links with brain function in greater detail, and new findings show that immune changes may differ by disorder type. A team involving researchers from Wroclaw…...

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New discovery helps identify colorectal cancer patients at risk for metastasis

11+ hour, 3+ min ago   (180+ words) The mucus forms a protective layer around the tumor, which reduces the effectiveness of cytostatic drugs and facilitates the spread of the cells into the abdominal cavity. This inverted structure not only helps tumor cells to migrate, but also enables…...

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Exposure to drought during pregnancy associated with higher risk of preterm birth

12+ hour, 25+ min ago   (538+ words) Our results show that drought is not only an environmental or agricultural phenomenon but also a potential determinant of maternal and child health. It is a clear example of planetary health: how changes in the climate and natural systems can…...