2+ day, 19+ hour ago  (441+ words) Scientists have found a way to drastically ramp up mouse immune responses to cancer along with flu and COVID-19 [1]. In this new MIT-led study published in Nature Biotechnology, the researchers tried moving upstream. They identified two factors that affect maturation…...

3+ day, 19+ hour ago  (842+ words) Most cardiovascular trials focus on lowering LDL cholesterol or reducing inflammation to slow disease progression. UDP-003 targets the root cause: toxic 7-ketocholesterol (7 KC) inside macrophages and soft plaques. It is designed to convert bloated foam cells back into healthy macrophages…...

4+ day, 18+ hour ago  (466+ words) This month, a group of researchers published an annual report on the clinical trials that are testing drugs for Alzheimer's disease. Overall, they reported an increase in the number of trials, with 158 drugs investigated across 192 trials [1]. Over the past decade,…...

5+ day, 19+ hour ago  (282+ words) We are super excited to share with you that today we released AI4 L " "AI for Practical Longevity, an open-source system that enables anyone to produce rigorous, evidence-based reviews of health and longevity interventions using frontier AI models. The 1. 0 release is…...

5+ day, 19+ hour ago  (769+ words) A new study suggests that GLP-1 receptor agonists do not affect muscle mass any more than weight loss caused by caloric restriction, and this appears to be true for strength as well [1]. GLP-1-based drugs, such as semaglutide and tirzepatide,…...

1+ week, 2+ day ago  (1201+ words) So, I switched back from chemistry to biology to identify those targets, and I moved to the US. I started as a research assistant working on three signaling pathways: the unfolded protein stress pathway, m TOR signaling, and stress signaling....

1+ week, 3+ day ago  (383+ words) In Aging Cell, researchers have elucidated the relationship between intestinal aging and age-related changes to the gut microbiome. To investigate this relationship, the authors first examined the intestines of 3-month-old and 24-month-old wild-type Black 6 mice. Unsurprisingly, like in other parts…...

1+ week, 5+ day ago  (373+ words) In a new study, the popular supplement creatine seemed to add to some of the beneficial effects of power training [1]. The authors chose two ways to deliver this kind of training. The first was elastic bands on land, as bands…...

1+ week, 6+ day ago  (548+ words) A new study has pit an advanced large language model against human physicians in tasks involving complex reasoning, treatment recommendations, and messy real-world patient records [1]. o1-preview included the correct diagnosis somewhere in its differential in 78. 3% of cases and named it…...

2+ week, 2+ day ago  (1195+ words) Since its founding in 2020, LIN has invested in 23 companies and helped facilitate more than $6. 7 million in capital deployment into longevity-focused startups worldwide. These companies span a wide range of areas, including cellular reprogramming, regenerative medicine, senotherapeutics, diagnostics, neurodegeneration, mitochondrial health,…...