News
First 3 D Structure of Malaria's "Moving Junction" Solves Infection Mystery
11+ hour, 46+ min ago (702+ words) Scientists visualized how the malaria parasite gains entry into RBCs through the ring-shaped moving junction, finding that the structure actively remodels the host cell's membrane, and also confirming that binders to the moving junction can block the parasite's ability to…...
In Huntington's Mouse, Optogenetic Activation of VIP Neurons Restores Brain Function
11+ hour, 58+ min ago (494+ words) The study is published in Nature in the paper, "Restoring cortical disinhibition improves Huntington's disease phenotypes." "This work shows that correcting specific imbalances in brain circuits can restore function, even in a complex neurodegenerative condition, and highlights the potential of…...
Biological Order Emerges from Tissue Boundaries, Drives Embryo Development
14+ hour, 21+ min ago (426+ words) Genetic Engineering and Biotechnology News In a new study in Nature Materials titled, "Boundary geometry controls a topological defect transition that determines lumen nucleation in embryonic development," researchers from European Molecular Biology Laboratory (EMBL) describe how interactions between tissue geometry…...
Trait Combining Key to More Effective Vector Production Hosts
16+ hour, 45+ min ago (526+ words) By Gareth John Macdonald Credit: Connect Images RF/Andrew Brookes/ Getty Images HEK293 cells may be the most common host used in viral vector production, but they are far from ideal, says the author of a new study, who argues that…...
Blueprint to Fill the Manufacturing Talent Gap
16+ hour, 45+ min ago (310+ words) Operator at the pilot plant at our Augusta Bio Facility. [Manus] To close the gap, Manus, a next-gen industrial biotechnology company, and Bio MADE have developed an apprenticeship program that can become a blueprint for other companies to develop their…...
Digitize or Fall Behind
16+ hour, 47+ min ago (151+ words) By Mike May, Ph D Credit: Image generated with Google Gemini Bioprocessing companies risk slowing scientific progress unless they embrace digital-data capture and greater collaboration, according to Alexander Seyf, CEO of Autolomous, a company developing digital manufacturing solutions for cell…...
Standardizing Personalized CRISPR Gene-Editing Therapies
16+ hour, 50+ min ago (423+ words) By Vivienne Raper, Ph D Credit: Design Cells/ i Stock / Getty Images Plus The revolutionary success of Baby KJ, the first patient to be treated with a personalized CRISPR gene-editing therapy, is spurring the industry to develop platforms for standardizing…...
Cytiva Completes Doubling of Utah Site's Liquid Media Production Capacity
1+ day, 11+ hour ago (671+ words) Pierre-Alain Ruffieux, Group Executive, Bioprocess, discusses recent announcements with GEN, including its use of AI and the FDA's AMT designation for the company's transient cell line Cytiva has completed an expansion of its Logan, UT, facility that effectively doubles its…...
Claude Science is Here, Antibiotics Designed by Text Prompt Among Applications
1+ day, 15+ hour ago (451+ words) Basecamp Research's antibiotic design and vaccine prediction AI models are now available through Anthropic's Claude Science By Fay Lin, Ph D Anthropic's life science partners are delivering applications. Basecamp Research is targeting global public health, where drug-resistant infections play a…...
i PSC-Derived Retinal Endothelial Cells Offer Platform for Studying Diseases
1+ day, 15+ hour ago (215+ words) Biomedical engineers at Duke University have for the first time used induced pluripotent stem cells (i PSCs) to grow specialized blood vessel cells critical to retinal health. When injected into mouse models of retinal disease, these "retinal endothelial cells" (i…...