23+ hour, 9+ min ago   (275+ words) We report the case of a 47-year-old Colombian woman with a persistent gait disorder beginning at 46 years of age. Neurological examination showed preserved strength, lower-limb spasticity, diffuse hyperreflexia, brisk jaw jerk, and a unilateral Hoffmann sign, without definite bulbar, respiratory,…...

23+ hour, 9+ min ago   (1473+ words) Acute psychosis during pregnancy creates a complex clinical scenario that requires simultaneous consideration of maternal psychiatric stabilization and fetal well-being. Guidance remains limited on the management of acutely psychotic pregnant patients who lack decision-making capacity and refuse care, particularly in…...

23+ hour, 9+ min ago   (175+ words) Background: Neonatal sepsis remains a leading cause of neonatal morbidity and mortality, particularly in resource-limited settings. Beyond infection itself, metabolic disturbances, such as abnormalities of blood glucose, may influence disease severity and outcome. Data on the prognostic significance of glycemic…...

23+ hour, 9+ min ago   (249+ words) Uterine adenosarcoma is a rare biphasic malignancy composed of benign epithelial and malignant stromal components. Adenosarcoma with sarcomatous overgrowth is an aggressive subtype associated with rapid progression and a poor prognosis. We report a case of uterine adenosarcoma with sarcomatous…...

23+ hour, 9+ min ago   (395+ words) Second-generation antipsychotics are effective for a range of pediatric psychiatric and behavioral conditions but are commonly associated with weight gain and metabolic dysfunction. Metformin is the most extensively studied pharmacological strategy for preventing or treating this adverse effect; however, the…...

23+ hour, 9+ min ago   (368+ words) Introduction Hemorrhagic stroke contributes disproportionately to stroke-related mortality and disability. This study examined national, regional, and sex-specific trends in hemorrhagic stroke mortality among Brazilian adults from 2000 to 2023 and assessed whether these trends changed during the COVID-19 pandemic. Materials and methods…...

23+ hour, 9+ min ago   (251+ words) Background Suicide mortality among young people has increased in Brazil, but prior studies have used heterogeneous age-group definitions and may have underestimated the burden by relying only on deaths coded as intentional self-harm. Methods This nationwide ecological time-series study used…...

23+ hour, 9+ min ago   (118+ words) Neurocysticercosis can present a diagnostic challenge in settings where it is not routinely suspected. Although endemic in many developing regions, it remains uncommon in Morocco, which may delay diagnosis. We report three cases illustrating its clinical and radiological variability in…...

23+ hour, 9+ min ago   (361+ words) Frail older adults approaching the end of life frequently receive multiple medications, diagnostic tests, hospital-based treatments, and procedures despite limited physiological reserve, shortened time-to-benefit, and changing goals of care. Low-value care in this setting is not defined solely by treatment…...

23+ hour, 9+ min ago   (342+ words) Background Intracranial ring-enhancing lesions are diagnostically heterogeneous because infective, neoplastic, demyelinating, and vascular etiologies may show overlapping conventional magnetic resonance imaging (MRI) appearances. This study evaluated and compared the diagnostic performance of post-contrast MRI and magnetic resonance spectroscopy (MRS) in…...