16+ min ago  (423+ words) Background and aim Acute myocardial infarction (AMI) remains a major cause of cardiovascular morbidity and mortality worldwide, particularly in low- and middle-income countries. Although right ventricular dysfunction (RVD) has emerged as an important determinant of outcomes in AMI, its relationship…...

46+ min ago  (351+ words) Severe traumatic brain injury (TBI) in pediatric patients is a time-dependent condition in which early airway management and rapid access to neurosurgical care are considered important to reduce the risk of secondary brain injury. The potential utility of Helicopter Emergency…...

35+ min ago  (270+ words) Head and neck cancers (HNCs) represent a heterogeneous group of malignancies with high morbidity and complex functional impairment. Despite advances in multimodal therapy, many patients present with advanced or incurable disease, demanding early integration of palliative care. To review the…...

1+ hour, 16+ min ago  (220+ words) Dysphagia is commonly attributed to intrinsic esophageal pathology; however, extrinsic compression from mediastinal processes remains an important and often underrecognized cause. We report the case of a 69-year-old man who presented with acute dysphagia due to food impaction. Esophagogastroduodenoscopy successfully…...

2+ hour, 41+ min ago  (287+ words) Postoperative cognitive dysfunction is a major clinical concern, particularly in elderly patients, leading to reduced quality of life and increased mortality. The impact of neuromuscular blockade reversal agents, such as sugammadex and neostigmine, on cognitive recovery remains uncertain. A systematic…...

1+ hour, 15+ min ago  (341+ words) Background Preconception care (PCC) improves maternal and child health outcomes by optimizing women's and couples' health before pregnancy through health education, supplementary medication, dietary modifications, and reducing preconception risk factors. In 2013, the World Health Organization (WHO) directed all nations to…...

1+ hour, 15+ min ago  (250+ words) Background and objective Molar incisor hypomineralization (MIH) and hypomineralized second primary molars (HPSM) are significant developmental dental anomalies that affect children's quality of life. This study aimed to determine the prevalence, distribution, and correlation between MIH and HPSM among children…...

2+ hour, 16+ min ago  (233+ words) Massive splenomegaly refers to a marked and clinically significant enlargement of the spleen beyond normal limits. Although uncommon, it is clinically significant because it may be associated with hematologic, infectious, infiltrative, malignant, or portal hypertensive disorders. Chronic hemolytic anemias are…...

3+ hour, 5+ min ago  (217+ words) Background Chronic kidney disease (CKD) is strongly associated with an increased incidence of cardiovascular complications. One of the mechanisms contributing to vascular damage in CKD is the decreased availability of nitric oxide (NO), an important regulator of vascular tone and…...

4+ hour, 26+ min ago  (224+ words) Breast cancer is the most common malignancy in women worldwide. A large proportion of breast cancer cases demonstrate human epidermal growth factor receptor 2 (HER2) overexpression. Trastuzumab emtansine (T-DM1) is an established therapy for HER2-positive metastatic breast cancer, though rare but serious adverse…...