8+ hour, 48+ min ago  (1737+ words) A potential novel therapeutic avenue for improving outcomes in cardiac disease involves targeting alarmins, endogenous danger signals capable of modulating both pathological inflammation and physiological repair9. Among these, High Mobility Group Box 1 (HMGB1) is the most extensively characterised9. HMGB1 can be actively secreted by…...

48+ min ago  (128+ words) Apr 09, 2026, 08: 00 ET Lead program DBXO-1 is designed to expand patient eligibility and improve durability ofresponse across major solid tumor indications While immuno-oncology therapies have transformed cancer treatment, a significant unmet need remains for broader patient populations. TCEs have shown clinical…...

8+ hour, 42+ min ago  (103+ words) The U. S. Food and Drug Administration (FDA) has released its Final Guidance on pre-market submission considerations for medical devices intended for uses associated with weight loss. As a reminder, FDA guidance documents do not establish legally enforceable requirements or responsibilities and…...

1+ hour, 46+ min ago  (339+ words) The Manila Times - Accelerated product approvals and significant time-to-market efficiency: Within three years since its listing, Kelun-Biotech has already secured approvals for 4 products across 8 indications, among which 3 products with 5 indications have been included in China's National Reimbursement Drug List (NRDL),…...

1+ hour, 59+ min ago  (56+ words) open PR. com We are establishing a secure connection. This website is using a security service to protect itself from online attacks. We are checking your browser to establish a secure connection and keep you safe. Performance & security by bunny....

3+ hour, 16+ min ago  (462+ words) Reg Med Net is part of Taylor & Francis Group. The therapy aims to overcome the limitations of current enzyme replacement therapy infusions and address safety concerns associated with stem cell therapy. ISP-001 utilizes the patient's own B cells to produce…...

2+ hour, 36+ min ago  (271+ words) New modeling study shows curative treatments may be viable in low-income settings if costs are scaled and societal benefits included Gene therapy for sickle cell disease (SCD) could be cost-effective in Uganda " but only if prices are dramatically reduced and…...

1+ hour, 33+ min ago  (229+ words) Learn about our commitments to making a positive impact on the world by providing access to innovative medicines, protecting the environment, and upholding high ethical standards. Novartis is hiring! Find open positions, learn more about our strategy and culture, and…...

4+ hour, 57+ min ago  (287+ words) Astellas Pharma Korea said Thursday that a tablet formulation of its prostate cancer treatment, Xtandi (enzalutamide), has been newly listed for national health insurance coverage from April 1. The newly covered Xtandi tablets are available in 40mg and 80mg doses. The 40mg tablet has…...

1+ hour, 33+ min ago  (189+ words) Ro adds Lilly's Foundayo to its weight-loss options days after FDA approval. Ro is expanding its weight-loss offering with the addition of Eli Lilly's newly approved oral GLP-1, Foundayo (orforglipron), giving patients a second daily pill alternative to injectable therapies…...