News
Scalable Embryonic Stem Cell Platform Enables Mitochondrial DNA Research in Mice
20+ hour, 12+ min ago (917+ words) Genetic Engineering and Biotechnology News Salk Institute scientists have developed a biological platform for studying mitochondrial DNA in physiology, adaptation, disease mechanisms, and therapeutic development. Headed by Ronald Evans, Ph D, professor and director of the Gene Expression Laboratory and…...
Single-Cell Atlas of Maternal'Fetal Interface Sheds Light on Pregnancy Complications
13+ hour, 38+ min ago (776+ words) Credit: Vladimir Zotov / 1288913695 / i Stock / Getty Images Plus Now, the human maternal'fetal interface has been mapped in unprecedented detail by scientists at the University of California, San Francisco (UCSF), revealing new cell types and providing insights into conditions such as…...
Organ-on-Chip Integrated Into Preclinical Glioblastoma Research
13+ hour, 56+ min ago (298+ words) Multilayer biochips for complex, 3 D in vitro cancer models [Dynamics42] Dynamic42 and EPO (Experimental Pharmacology and Oncology), both based in Germany, report that they are addressing the limited availability of preclinical models in brain cancer research by forming a strategic collaboration that…...
Neuroblastoma Tumor Growth in Mice Suppressed by Blocking Enzyme to Inhibit m TOR Signaling
19+ hour, 13+ min ago (249+ words) Neuroblastoma is the most common tumor among children under a year of age, and while in its gentlest form neuroblastoma can regress on its own, it can also take an aggressive form, with high-risk neuroblastoma carrying a five-year survival rate…...
Redefining Bioprocessing Using Reservoirs of Biochemical Diversity
22+ hour, 32+ min ago (263+ words) By Mike May, Ph D Credit: Penpak S. / Getty Images In the global race to improve how medicines are made, scientists are turning to an unlikely source of innovation: the microscopic life thriving in some of the harshest soils on Earth....
Faster Process Development via "Transfer Learning
1+ day, 2+ hour ago (540+ words) By Gareth John Macdonald Credit: Robert Essel NYC/ Getty Images An emerging artificial intelligence technique called "transfer learning" could help drug makers use data to speed up the development of biopharmaceutical manufacturing processes, according to new analysis. In transfer learning,…...
Plant Molecular Farming Comes of Age
22+ hour, 32+ min ago (284+ words) Credit: sinology/ Getty Images Plant molecular farming (PMF) may seem like a bold option for companies accustomed to mammalian or microbial systems, but recent advances have transformed plant-based bioproduction into serious, scalable biomanufacturing platforms able to produce even complex biologics…...
Forecasting Protein Aggregation with an Improved Algorithm
22+ hour, 31+ min ago (384+ words) By Vivienne Raper, Ph D A new, improved algorithm for studying protein aggregation could help biologics manufacturers design better-performing products with less experimental effort. The software, developed by scientists based in Barcelona, offers the ability to analyze the aggregation of…...
Childhood Dementia Explained by Synaptic Dysfunction, Opens New Therapies
22+ hour, 21+ min ago (353+ words) In Australia, an estimated 1400 children currently live with childhood dementia, with hundreds of thousands of cases worldwide. Sanfilippo syndrome is a rare genetic condition that causes fatal brain damage. Children typically reach early developmental milestones before rapidly losing cognitive skills,…...
New Single'Cell Platform Tracks RNA and Protein in Immune Signaling
1+ day, 3+ hour ago (928+ words) Genetic Engineering and Biotechnology News A new single'cell sequencing method is giving researchers a clearer view of how immune cells actually behave'capturing not just what they plan to do, but what they are doing in real time. The platform, called…...